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Showing posts from March, 2017

New genetic links underlying progressively blinding eye disease identified

Three novel genomic loci -- distinct stretches of genetic material on chromosomes -- linked to Fuchs endothelial corneal dystrophy (FECD), which often clusters in families and is roughly 39 percent heritable, have been identified by researchers. Using genome-wide association data, they deepen understanding of Fuchs endothelial corneal dystrophy, the most common cause for corneal transplants.

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Time delays in vending machines prompt healthier snack choices

Delaying access to tempting, high-calorie foods and snacks in vending machines potentially can shift people's choices to purchase less desired, but healthier snack options, new research suggests.

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Stem cells help explain varied genetics behind rare neurologic disease

Researchers have successfully grown stem cells from children with a devastating neurological disease to help explain how different genetic backgrounds can cause common symptoms. They identified individual and shared defects in the cells that could inform treatment efforts.

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Making bones stronger

New treatments for osteoporosis are desperately needed. Now scientists report estimates of potentially the most effective dosage of a particular peptide, with results that could raise density levels in badly degraded bones back to healthy levels.

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Listeria bacteria can hide inside tissue of romaine lettuce, study reveals

The bacteria Listeria monocytogenes can live inside the tissue of romaine lettuce, researchers have found, suggesting that conventional post-harvest sanitization practices might not be sufficient to kill the potentially lethal pathogen.

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How to Rebuild Atlanta’s Collapsed Freeway. Like, Now

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Money is always a good incentive ... The post How to Rebuild Atlanta's Collapsed Freeway. Like, Now appeared first on WIRED.

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Blood test unlocks new frontier in treating depression

For the first time, doctors can determine which medication is more likely to help a patient overcome depression, according to research that pushes the medical field beyond what has essentially been a guessing game of prescribing antidepressants.

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Apixaban superior to warfarin for reducing brain bleeds in patients with AFib

Patients with atrial fibrillation showed a substantially reduced risk of dangerous bleeding in the brain, known as intracranial hemorrhage, when taking the newer anticoagulant apixaban compared to those taking warfarin. The study also showed that taking aspirin increased the risk of intracranial hemorrhage, especially in older patients.

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Breakthrough in antioxidant enzyme linked to jaundice

A research team has investigated biliverdin reductase, the enzyme producing bilirubin -- a substance linked with jaundice -- from biliverdin (BV). Two BV molecules were found at the enzyme reaction site, in an unusual stacked arrangement. Mutation experiments confirmed which enzyme amino acid was necessary for bilirubin production. In the proposed mechanism, this amino acid transfers hydrogen to one BV molecule, using the other BV as a conduit. This aids the search for anti-jaundice drugs.

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Medication history for patients on blood thinners is critical to EMS

One change to field triage guidelines for emergency medical services (EMS) responding to older adults with head trauma could make a 'clinically important improvement over usual care,' according to new research.

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Novel vulnerabilities in dengue virus discovered

Hidden vulnerabilities on the surface of the dengue virus have been found by researchers. This discovery offers exciting possibilities for development of drugs to target these weak spots for treatment of dengue and related viruses such as Zika.

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High doses of vitamin C to improve cancer treatment passes human safety trial

Clinical trials found that it is safe to regularly infuse brain and lung cancer patients with 800-1,000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments. The researchers also show pathways by which altered iron metabolism in cancer cells, and not normal cells, lead to increased sensitivity to cancer cell killing caused by high dose vitamin C.

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Molecular therapy set to protect at-risk patients against heart attack and stroke

Even a single dose of a specific ribonucleic acid molecule, known as a small interfering RNA (siRNA), offers patients at high risk of cardiovascular disease long-lasting protection against high LDL cholesterol -- one of the main risk factors for heart attack and stroke -- conclude researchers.

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Exploring New Galaxies

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This week, the Samsung Galaxy S8, the Baselworld watch convention, and revisiting the first tablet PC. The post Exploring New Galaxies appeared first on WIRED.

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Joss Whedon Could Make a Great Batgirl Movie, But He Shouldn’t

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Joss Whedon is in talks to write and direct a Batgirl movie, but there are better things he could be doing with his talents. The post Joss Whedon Could Make a Great Batgirl Movie, But He Shouldn’t appeared first on WIRED.

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Insomnia associated with increased risk of heart attack and stroke

Insomnia is associated with increased risk of heart attack and stroke, according to new research.

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Experimental small molecule shows potential in preventing meth relapse

The reason methamphetamine users find it so hard to quit -- 88 percent of them relapse, even after rehab -- is that meth takes advantage of the brain's natural learning process, say scientists.

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Helping the retina regenerate

A new report gives recommendations for regenerating retinal ganglion cells (RGCs), crucial neurons in the back of the eye that carry visual information to the brain.

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What’s Coming in the Next Game of Thrones Season? Look at the Clothes

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Winter is here—and so are a lot of monochromatic outfits. The post What’s Coming in the Next Game of Thrones Season? Look at the Clothes appeared first on WIRED.

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Hair testing shows high prevalence of new psychoactive substance use

Hair samples from 80 young adults outside of NYC nightclubs and dance festivals were tested for 82 drugs and metabolites in a new study using ultra-high performance liquid chromatography-tandem mass spectrometry.

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Risky alcohol consumption can increase at time of retirement

Every tenth employee increases their alcohol consumption to risky levels at the time of retirement from full-time employment. However, the increase seems to be temporary as risky drinking often decreases during the retirement. For most pensioners, alcohol consumption remains below the risk levels before and after retirement, a new Finnish study concludes.

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New treatment for antibiotic resistant bacteria and infectious disease

A new treatment pathway for antibiotic resistant bacteria and infectious diseases with benefits for patients and health care providers has been described in a new report.

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These five tests better predict heart disease risk

Five simple medical tests together provide a broader and more accurate assessment of heart-disease risk than currently used methods, cardiologists have found.

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Vaginal bacteria can trigger recurrent UTIs, study shows

A kind of bacteria found in the vagina may trigger recurrent UTIs, according to researchers. The findings help explain why sexual activity is associated with UTIs. When it gets into the bladder, the vaginal bacteria Gardnerella vaginalis causes dormant E. coli from a previous infection to start multiplying again, causing another UTI. Gardnerella may also contribute to more serious kidney infections, the study suggests.

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Rarely studied gene USF3 plays role in predisposition to thyroid cancer

A faulty, rarely studied gene called USF3 may predispose individuals to thyroid cancer, suggests scientists in a new report.

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Music therapy reduces pain in spine surgery patients

Music therapy has been found to decrease pain in patients recovering from spine surgery, compared to a control group of patients who received standard postoperative care alone.

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Tiny bioengineered blood vessel grafts aid delicate microsurgeries

Scientists have been working diligently to create engineered tissue implants to repair or replace damaged or diseased tissue and organs; but their success hinges on the ability to build a sturdy connection linking the implant’s blood vessels and the patient’s existing vasculature. Now researchers have created segments of engineered blood vessels to address this critical issue.

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Yup, Rockets Need Insurance, Too. But Way More Than the Feds Think

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A launch cataclysm could end up costing the federal rocket insurance program way more than it currently estimates. The post Yup, Rockets Need Insurance, Too. But Way More Than the Feds Think appeared first on WIRED.

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Destiny 2 Needs to Get a Lot Weirder Than Its First Trailer

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The sequel is coming this September—but while its new trailer is a fun first look, it's a parade of missed opportunities. The post Destiny 2 Needs to Get a Lot Weirder Than Its First Trailer appeared first on WIRED.

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Step Inside a Saudi Rehab Prison for Jihadists

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Government officials embrace a unique method of reform. The post Step Inside a Saudi Rehab Prison for Jihadists appeared first on WIRED.

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Why You Should Put Your Supercomputer in Wyoming

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A new supercomputer for the National Center for Atmospheric Research gets to work studying climate and solar flares—and prepares for a bunch of new neighbors. The post Why You Should Put Your Supercomputer in Wyoming appeared first on WIRED.

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Typeshift Enlightens Word Nerds With Masterful Game Design

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The latest from smartphone smart-game guru Zach Gage is an addictive riff on crosswords and a master class in smart game design. The post Typeshift Enlightens Word Nerds With Masterful Game Design appeared first on WIRED.

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Boeing’s Test Protocol for New Planes Is as Brutal As You’d Hope

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Today will be easy. Tomorrow, not so much. The post Boeing's Test Protocol for New Planes Is as Brutal As You'd Hope appeared first on WIRED.

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Silicon Valley’s Plot to Reinvent the Dreaded Conference Call

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Meetings have always been torture. But now the tech industry is threatening to make them work. The post Silicon Valley's Plot to Reinvent the Dreaded Conference Call appeared first on WIRED.

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Hey Tech Giants: How About Action on Diversity, Not Just Reports?

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Maybe the best way to show commitment to change is to actually change. The post Hey Tech Giants: How About Action on Diversity, Not Just Reports? appeared first on WIRED.

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Elon Musk Isn’t the Only One Trying to Computerize Your Brain

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These companies are applying the Silicon Valley playbook to neuroscience. The post Elon Musk Isn’t the Only One Trying to Computerize Your Brain appeared first on WIRED.

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Yes, Spider-Man Can Jump 6 Meters Onto a Moving Ferry. Physics Says So

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Let's do some video analysis (homework included). The post Yes, Spider-Man Can Jump 6 Meters Onto a Moving Ferry. Physics Says So appeared first on WIRED.

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For Google, the AI Talent Race Leads Straight to Canada

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America's biggest tech companies are remaking the internet through artificial intelligence—and they're looking north to Canada to advance AI itself. The post For Google, the AI Talent Race Leads Straight to Canada appeared first on WIRED.

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Marco Rubio Says Hack Attempts From Russia Targeted Him, Too

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Attempted intrusions against any senator aren't surprising. But they're a reminder election hacking shouldn't be a partisan issue. The post Marco Rubio Says Hack Attempts From Russia Targeted Him, Too appeared first on WIRED.

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Devin Nunes: A Running Timeline of His Odd Surveillance Claims and White House Ties

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The House Intelligence Committee chair has had himself quite a week. The post Devin Nunes: A Running Timeline of His Odd Surveillance Claims and White House Ties appeared first on WIRED.

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Getting a leg up: Hand task training transfers motor knowledge to feet

The human brain's cerebellum controls the body's ability to tightly and accurately coordinate and time movements as fine as picking up a pin and as muscular as running a foot race. Now, researchers have added to evidence that this structure also helps transfer so-called motor learning from one part of the body to another.

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NIH funding helps generate private-sector patents

Research grants issued by the National Institutes of Health (NIH) contribute to a significant number of private-sector patents in biomedicine, according to a new study. The study examines 27 years of data and finds that 31 percent of NIH grants, which are publicly funded, produce articles that are later cited by patents in the biomedical sector.

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Previous exposure to flaviviruses increases effects of Zika

Prior infection with dengue or West Nile virus can enhance the effects of Zika infection, a new study using human samples tested in mice finds.

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Aging: Cell coordination breakdown

Scientists have resolved a key question in aging research by showing how mouse immune cells of different ages respond to stimulation. Study demonstrates weaker response of older cells is due to their coordination breaking down, making their response to immune stimulation more variable. Single-cell sequencing technology allows scientists to profile individual cells independently to view cellular activity in high resolution.

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Triple-threat cancer-fighting polymer capsules for guided drug delivery

Chemists have designed triple-threat cancer-fighting polymer capsules that bring the promise of guided drug delivery closer to preclinical testing. These multilayer capsules show three traits that have been difficult to achieve in a single entity. They have good imaging contrast that allows detection with low-power ultrasound, they can stably and efficiently encapsulate the cancer drug doxorubicin, and both a low- and higher-power dose of ultrasound can trigger the release of that cargo.

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A Silicon Valley Lawmaker’s $1 Trillion Plan to Save Trump Country

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Silicon Valley's newest member of Congress wants lawmakers to embrace one of tech's favorite ideas: a basic income to counter the impact of automation. The post A Silicon Valley Lawmaker's $1 Trillion Plan to Save Trump Country appeared first on WIRED.

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Valerian’s Biggest PR Problem: It Did Everything First

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To sell Luc Besson's latest sci-fi epic, his studio has to make it look familiar—but also new. The post Valerian's Biggest PR Problem: It Did Everything First appeared first on WIRED.

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Big Cable’s Case for Selling Your Data Doesn’t Hold Up

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ISPs claim they want a level playing field, but it's already tilted in their favor. The post Big Cable's Case for Selling Your Data Doesn't Hold Up appeared first on WIRED.

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The World’s Biggest Porn Site Goes All-In on Encryption

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Now that Pornhub's going HTTPS, your private browsing will be a lot more private. The post The World's Biggest Porn Site Goes All-In on Encryption appeared first on WIRED.

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The Fanged Fish That Drugs Its Enemies With Opioids

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Researchers reveal what makes the fang blenny's venom so unique: It's packed with opioid peptides. The post The Fanged Fish That Drugs Its Enemies With Opioids appeared first on WIRED.

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Larger doses of vitamin C may lead to a greater reduction in common cold duration

The relationship between vitamin C dosage and its effects on the duration of the common cold symptoms may extend to 6-8 grams per day.

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Confessions of Presidential Joke Writer Jon Lovett

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"We can make fun and we can fight and we can do it through jokes and through comedy, but it has to be about more than why people are reprehensible." The post Confessions of Presidential Joke Writer Jon Lovett appeared first on WIRED.

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An App That Tracks Your Movement to Help You Relax, Even in the Back of a Cab

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Sway is the latest in a recent spate of meditation apps designed to encourage mindfulness. The post An App That Tracks Your Movement to Help You Relax, Even in the Back of a Cab appeared first on WIRED.

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Review: Earin M-1 Wireless Earbuds

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Apple's AirPods aren't the only wireless earbud game in town. The post Review: Earin M-1 Wireless Earbuds appeared first on WIRED.

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