Wednesday, November 30, 2016

Drug delivery modification sidesteps allergic responses

Biomedical engineers have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials. Polyethylene glycol, commonly known as PEG, is a polymer commonly found in commercial products from toothpaste to cosmetics, and also in pharmaceuticals. PEG is used as a thickener, solvent, softener and moisture-carrier, but it can also be attached to active drugs in the bloodstream to slow the body's clearing of them, greatly lengthening the duration of their effects.

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