When T cells encounter an antigen, they proliferate and produce various types of daughter cells. Medical researchers have now refuted the prevailing hypothesis that this immune response is largely predetermined by the individual structure of the T cell receptor. Instead, the influence of the T cell receptor can be described only in probabilistic terms. Such mathematical models may help to improve the design of future vaccination strategies.
https://www.sciencedaily.com/releases/2017/07/170731114637.htm